Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis

Key Inclusion Criteria:

To be eligible for inclusion into the study, a patient must meet the following criteria:

1. Subject has clinically confirmed diagnosis of active AD;
2. Subject has chronic pruritus related to AD;
3. Subject has moderate to severe pruritus;
4. Female subject is not pregnant or nursing during any period of the study.

Key Exclusion Criteria:

A patient will be excluded from the study if any of the following criteria are met:

1. Subject has clinically infected AD;
2. Subject has pruritus attributed to a cause other than AD;
3. Subject has any clinically significant medical condition or physical/laboratory/ECG/vital signs abnormality that would, in the opinion of the investigator, put the subject at undue risk or interfere with interpretation of study results.