For Healthcare Professionals

DETERMINE: Detemir vs NPH

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About the study

The purpose of the study is to compare rates of neonatal hypoglycemia with maternal NPH vs determir use.
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Who can take part

You may be eligible to participate in the study if you meet the following criteria:

INCLUSION CRITERIA

Inclusion Criteria:

Inclusion criteria will include pregnant women with pre-existing T2DM and GDM who requiring insulin to manage their blood sugars in pregnancy.

EXCLUSION CRITERIA

Exclusion Criteria:

  1. Multiple Gestation
  2. Type 1 Diabetes mellatus
  3. Age < 18
  4. Known or suspected hypersensitivity to NPH or insulin detemir
  5. Known fetal major malformations
  6. Chronic renal or hepatic insufficiency
  7. Known to be HIV, Hepatitis B, or Hepatitis C positive
  8. Indication for planned premature delivery (placenta accrete, or prior classical cesarean delivery)
  9. Insulin dependent before conception
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Study Locations

Enter your ZIP code/Postal code/PIN code to locate study sites near you:

How to Apply


Contact the study center to learn if this study is a good match for you.

Study’s details


Contition

Gestational Diabetes,Diabetes Mellitus, Type 2

Age (in years)

18+

Phase

Phase 2

Participants needed

336

Est. Completion Date

Jun 30, 2025

Treatment type

Interventional


Sponsor

University of California, Los Angeles

ClinicalTrials.gov identifier

NCT05124457

Study number

DETERMINE

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