Tissue Characterization and Primary Percutaneous Coronary Intervention Guidance Using Intravascular Ultrasound
About the study
This prospective, single arm, observational cohort study is designed to assess the safety and efficacy of (high-definition) intravascular ultrasound (HD-IVUS) as guidance for primary percutaneous coronary intervention (PCI) and to assess culprit lesion plaque characteristics and thrombus morphology in patients with ST-elevation myocardial infarction (STEMI).
Objectives:
To assess clinical outcomes after IVUS-guided primary PCI in STEMI patients.
To assess IVUS-guided optimization in STEMI patients.
To assess culprit lesion plaque characteristics in STEMI patients with HD-IVUS.
To assess and quantify thrombus in STEMI patients with HD-IVUS.
To explore HD-IVUS derived predictors for clinically relevant aspiration thrombectomy.
Who can take part
You may be eligible to participate in the study if you meet the following criteria:
INCLUSION CRITERIA
Inclusion Criteria:
- Native coronary artery culprit lesion, angiographically
- Culprit vessel reference diameter ≥ 2.25 mm, angiographically
EXCLUSION CRITERIA
Exclusion Criteria:
- Cardiogenic shock
- Presentation > 12 hours after symptom onset
Study Locations
Enter your ZIP code/Postal code/PIN code to locate study sites near you:
How to Apply
Contact the study center to learn if this study is a good match for you.
Study’s details
Contition
ST Elevation Myocardial Infarction,Acute Myocardial Infarction,Coronary Artery Disease,Percutaneous Coronary Intervention,Intravascular Ultrasound,Thrombus
Age (in years)
18+
Participants needed
200
Est. Completion Date
Feb 2, 2023
Treatment type
Observational
Sponsor
Erasmus Medical Center
ClinicalTrials.gov identifier
NCT05007535
Study number
SPECTRUM
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