For Healthcare Professionals

The clonoSEQ® Watch Registry


About the study

This is a prospective, multicenter, observational study of adult patients with a diagnosis of acute lymphoblastic leukemia (ALL), multiple myeloma (MM), chronic lymphocytic leukemia (CLL), or non-Hodgkin lymphoma (NHL). This study will enroll up to 528 patients in up to 50 sites in the United States and collect data with regard to use of the clonoSEQ MRD assay in the management of lymphoid malignancies.

Who can take part

You may be eligible to participate in the study if you meet the following criteria:


Inclusion Criteria:

  1. Patients must be able to provide written informed consent
  2. A decision has been made by the treating provider to use the clonoSEQ Assay as part of routine clinical care
  3. Age ≥ 18 years;

Documented hematologic malignancy (any of the below):

  1. MM
  2. ALL (B and T-cell subtypes)
  3. B-cell NHL (all sub types)
  4. CLL
  5. Other lymphoid malignancies (upon review and approval by study chair)


Exclusion Criteria:

Patients must not meet any of the following criteria in order to be enrolled into the study:

  1. Concurrent enrollment in a clinical trial where treatment decisions and patterns are dictated per protocol
  2. A decision has been made by the treating provider to not use the clonoSEQ Assay as part of routine clinical care

pin location

Study Locations

Enter your ZIP code/Postal code/PIN code to locate study sites near you:

How to Apply

Contact the study center to learn if this study is a good match for you.

Study’s details


Non-hodgkin Lymphoma,Acute Lymphoblastic Leukemia, Adult B-Cell,Chronic Lymphocytic Leukemia,Multiple Myeloma

Age (in years)


Participants needed


Est. Completion Date

Dec 31, 2024

Treatment type

Observational [Patient Registry]


Adaptive Biotechnologies identifier


Study number


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