For Healthcare Professionals

Study of BMS-986315 Alone and in Combination With Nivolumab or Cetuximab in Participants With Advanced Solid Tumors


About the study

The purpose of this study is to evaluate BMS-986315 alone and in combination with nivolumab or cetuximab in participants with advanced solid tumors.

Who can take part

You may be eligible to participate in the study if you meet the following criteria:


  1. Participants must have histologic confirmation of advanced (metastatic, recurrent, and/or unresectable) squamous cell carcinoma of the head and neck (SCCHN), nonsmall cell lung cancer (NSCLC), or renal cell cancer (RCC) with measurable disease per RECIST 1.1
  2. Participants expected to have received standard of care therapies including an available PD-(L)1 inhibitor
  3. Eastern cooperative oncology group performance status of 0 or 1
  4. Women of childbearing potential must agree to follow methods of contraception


  1. Participants with active, known or suspected autoimmune disease
  2. Participants with a condition requiring systemic treatment with either corticosteroids or other immunosuppressive medications
  3. Uncontrolled or significant cardiovascular disease
  4. History of or with active interstitial lung disease or pulmonary fibrosis
  5. Prior participation in anti-natural killer cell receptor (anti-NKG2A) clinical study
  6. History of allergy or hypersensitivity to study drug components Other protocol-defined inclusion/exclusion criteria apply
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Study Locations

Enter your ZIP code/Postal code/PIN code to locate study sites near you:

How to Apply

Contact the study center to learn if this study is a good match for you.
Phone iconCall 855-907-3286Email iconEmail Study Center

Study’s details


Advanced Solid Tumor

Age (in years)

18 - 200


Phase 1/Phase 2

Participants needed


Est. Completion Date

May 2025

Treatment type



Bristol-Myers Squibb identifier


Study number


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