For Healthcare Professionals

Avelumab Program Rollover Study


About the study

The main purpose of this study is to monitor the safety and tolerability of avelumab in participants with solid tumors who continue treatment with avelumab under the same treatment regimen as in the parent avelumab study.

Who can take part

You may be eligible to participate in the study if you meet the following criteria:


Inclusion Criteria:

Participants under enrollment and treatment in an avelumab clinical study under the sponsorship of EMD Serono Research & Development Institute, Inc. / Merck KGaA, Darmstadt, Germany

  1. Merck Serono Co., Ltd (Japan)
  2. Participants currently enrolled in an avelumab parent study and are on active treatment with avelumab or in long-term survival follow-up after treatment
  3. Participants on active treatment must agree to continue to use highly effective contraception (that is, methods with a failure rate of less than 1% per year) for both male and female participants if the risk of conception exists
  4. Other protocol defined inclusion criteria could apply.


Exclusion Criteria:

  1. Participants who are pregnant or breastfeeding
  2. Participants still on active treatment: Known hypersensitivity to any of the study intervention ingredients
  3. Participant has been enrolled in the comparator arm of avelumab parent study
  4. Participant has been withdrawn from avelumab parent study for any reason
  5. Any other reason that, in the opinion of the Investigator, precludes the participant from participating in the study
  6. Other protocol defined exclusion criteria could apply.

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Study Locations

Enter your ZIP code/Postal code/PIN code to locate study sites near you:

How to Apply

Contact the study center to learn if this study is a good match for you.

Study’s details


Solid Tumors

Age (in years)



Phase 3

Participants needed


Est. Completion Date

Jan 28, 2024

Treatment type



EMD Serono identifier


Study number


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