For Healthcare Professionals

First Real-world Data on Unresectable Stage III NSCLC Patients Treated With Durvalumab After Chemoradiotherapy

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About the study

This is a non-interventional/observational cohort of NSCLC unresectable stage III patients treated with durvalumab. The study will be carried out as a retrospective review of established medical records for a subset of unresectable stage III patients treated with durvalumab.
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Who can take part

You may be eligible to participate in the study if you meet the following criteria:

INCLUSION CRITERIA

Inclusion Criteria:


  1. Written informed consent or any locally required authorisation obtained from the patient prior to performing any protocol-related procedures
  2. Age ≥ 18 years at time of study entry or adult according to each country regulations for age of majority
  3. Patients must have histologically or cytologically documented diagnosis of NSCLC with a locally advanced, or locally recurrent, unresectable (stage III) disease (according to American Joint Committee on Cancer [AJCC] lung cancer edition 7 or 8)
  4. Patients must have been enrolled in one of the durvalumab EAPs Patients must have been treated with at least one dose of durvalumab within the EAP prior to the study entry and between start of EAP in the country, from September 2017 or later up to end of EAP enrolment or MA + three months (estimated as maximum to 30 December 2018) (whichever occurs earlier).

EXCLUSION CRITERIA

Patients who die during the EAP are eligible to enter in the study when local laws allow for a consent waiver, if all other inclusion/exclusion criteria are met.


Exclusion Criteria:


-Patients treated with durvalumab in clinical studies prior to the index date (first dose of durvalumab received within the EAP).


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Study Locations

Enter your ZIP code/Postal code/PIN code to locate study sites near you:

How to Apply


Contact the study center to learn if this study is a good match for you.

Study’s details


Contition

NSCLC

Age (in years)

18 - 130

Participants needed

1159

Est. Completion Date

Dec 20, 2023

Treatment type

Observational


Sponsor

AstraZeneca

ClinicalTrials.gov identifier

NCT03798535

Study number

D4194R00005

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