Lifetech LAmbre™ Left Atrial Appendage (LAA) Closure System Post-Market Clinical Follow-up

Inclusion Criteria:

1. Patients must be at least 18 years of age;
2. Patients with non-valvular paroxymal, persistent or permanent atrial fibrillation with long-term sustainability scheduled for interventional LAA closure;
3. Patient characteristics consistent with the corresponding IFU and sizing guidelines;
4. The patient or legally authorized representative has been informed of the nature of the study, agrees to its provisions and has provided written informed consent, approved by the appropriate Ethics Committee (EC);

The patient agrees to comply with requirements of the study including the 3 year follow-up.

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Exclusion Criteria:

1. Any contra-indication mentioned in the corresponding IFU;
2. Currently participating in other investigational drug- or device studies;
3. Patient who is pregnant, planning to become pregnant or breast feeding;
4. Patients cannot tolerate transoesophageal echocardiogram (TEE).