Evaluate F901318 Treatment of Invasive Fungal Infections in Patients Lacking Treatment Options

Inclusion Criteria:

1. Male and female aged at least 18 years, or male and female aged 16 years or 17 years and who weigh at least 40 kg whom have given informed consent
2. Ability and willingness to comply with the protocol.
3. Able to take oral medication
4. Female must be non-lactating and at no risk of pregnancy
5. Male with female partners of childbearing potential must either abstain from sexual intercourse or use a highly effective means of contraception
6. Patients with invasive fungal disease
7. Patients who have limited alternative treatment options

Exclusion Criteria:

1. Women who are pregnant or breastfeeding.
2. Known history of allergy, hypersensitivity, or any serious reaction to any component of the study drug.
3. Patients with chronic aspergillosis, aspergilloma or allergic bronchopulmonary aspergillosis.
4. HIV infection but not currently receiving antiretroviral therapy.
5. Patients with a medical condition that may jeopardize adherence to the protocol or may cause unacceptable additional risk to the patient
6. Previously enrolled patients or patients enrolled in any clinical trial within the last 30 days
7. Patients receiving treatment limited to supportive care due to predicted short survival time.
8. Prohibited concomitant medications.

Any exclusion criteria required by local regulatory authorities.