For Healthcare Professionals

A Study of LY3039478 in Japanese Participants With Advanced Solid Tumors

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About the study

The purpose of this study is to evaluate the tolerability of the study drug LY3039478 in Japanese participants with advanced solid tumors.
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Who can take part

You may be eligible to participate in the study if you meet the following criteria:

INCLUSION CRITERIA

Inclusion Criteria:


  1. Histological or cytological evidence of a diagnosis of solid tumor that is advanced and/or metastatic.
  2. In the judgment of the investigator, participants must be appropriate candidates for experimental therapy after available standard therapies have failed or for whom standard therapy is not appropriate.
  3. Performance status of ≤1 on the Eastern Cooperative Oncology Group (ECOG) scale.
  4. Adequate organ function, including hematologic, hepatic, and renal.
  5. Estimated life expectancy of ≥12 weeks.

EXCLUSION CRITERIA

Exclusion Criteria:


  1. Received previous therapy for cancer within 14 or 21 days of the initial dose of study drug for a nonmyelosuppressive or myelosuppressive agents, respectively.
  2. Have serious preexisting medical conditions.
  3. Have current or recent (within 3 months of study drug administration) gastrointestinal disease with chronic or intermittent diarrhea.
  4. Have an active bacterial, fungal, and/or known viral infection.
  5. Have known acute or chronic leukemia or current hematologic malignancies that may affect the interpretation of results.

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Study Locations

Enter your ZIP code/Postal code/PIN code to locate study sites near you:

How to Apply


Contact the study center to learn if this study is a good match for you.

Study’s details


Contition

Advanced Solid Tumor

Age (in years)

20+

Phase

Phase 1

Participants needed

12

Est. Completion Date

Oct 31, 2023

Treatment type

Interventional


Sponsor

Eli Lilly and Company

ClinicalTrials.gov identifier

NCT02836600

Study number

I6F-JE-JJCC

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