A Study of LY3039478 in Japanese Participants With Advanced Solid Tumors
About the study
The purpose of this study is to evaluate the tolerability of the study drug LY3039478 in Japanese participants with advanced solid tumors.
Who can take part
You may be eligible to participate in the study if you meet the following criteria:
INCLUSION CRITERIA
Inclusion Criteria:
- Histological or cytological evidence of a diagnosis of solid tumor that is advanced and/or metastatic.
- In the judgment of the investigator, participants must be appropriate candidates for experimental therapy after available standard therapies have failed or for whom standard therapy is not appropriate.
- Performance status of ≤1 on the Eastern Cooperative Oncology Group (ECOG) scale.
- Adequate organ function, including hematologic, hepatic, and renal.
- Estimated life expectancy of ≥12 weeks.
EXCLUSION CRITERIA
Exclusion Criteria:
- Received previous therapy for cancer within 14 or 21 days of the initial dose of study drug for a nonmyelosuppressive or myelosuppressive agents, respectively.
- Have serious preexisting medical conditions.
- Have current or recent (within 3 months of study drug administration) gastrointestinal disease with chronic or intermittent diarrhea.
- Have an active bacterial, fungal, and/or known viral infection.
- Have known acute or chronic leukemia or current hematologic malignancies that may affect the interpretation of results.
Study Locations
Enter your ZIP code/Postal code/PIN code to locate study sites near you:
How to Apply
Contact the study center to learn if this study is a good match for you.
Study’s details
Contition
Advanced Solid Tumor
Age (in years)
20+
Phase
Phase 1
Participants needed
12
Est. Completion Date
Oct 31, 2023
Treatment type
Interventional
Sponsor
Eli Lilly and Company
ClinicalTrials.gov identifier
NCT02836600
Study number
I6F-JE-JJCC
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